The Presidential Daily Brief


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    CRISPR’s About to Get a Massive Upgrade

    Oh, you thought targeted gene editing was futuristic? Welcome to 2018: Research teams around the world are looking beyond CRISPR, DNA editing tech’s first generation, to the next leaps forward. Those include the potential to transform nucleotides, which could correct mutations, anti-CRISPR proteins that act as an off-switch for the unruly process, and new enzymes that target RNA that governs cell operation. These technologies could help treat short-term illnesses while enabling gene drives, or modifications that might proliferate, say, through a mosquito population and make it malaria-free.

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