Many lessons can be learned from the outbreak that has claimed 3,400 lives in West Africa. Chief among them is the critical role played by governments and organizations with the experience and means to make a difference. We faced more than 350 federally declared disasters during my time as DHS secretary, including the H1N1 outbreak, and I’ve learned that effective disaster response requires an all-of-community approach. Obviously, little had been done in the region to adequately prepare for an Ebola outbreak; now we must play catch-up. As the traveler in Dallas reminds us, Ebola is truly a global crisis and countries around the world must work to stem this serious threat to global health.