Serena and Venus Williams were all set to face one another in round three at Roland Garros. But two relative unknowns have put the legendary sisters on an early flight home. First, teenager Anna Schmiedlova knocked off 29th-seeded Venus. Then, in a far bigger shock, 20-year-old Garbine Muguruza crushed top seed Serena, 6-2, 6-2, the number one’s worst singles loss at a Grand Slam. After more than a decade of total dominance, is the Williams era finally drawing to a close?